Tumour immunology - immunology tumor

Tumour cells are usually not recognized and killed by the immune system. There are two main causes. The first is failure to express molecules such as HLA and costimulatory B7 molecules which are required for activation of cytotoxic, or 'killer', T lymphocytes, since expression of these 'costimulatory' molecules following gene transfection may augment an immune response. Secondly, tumours may also actively secrete immunosuppressive cytokines and cause a generalized immunosuppression, leading for example to the reactivation of latent herpes zoster in shingles associated with malignancy.

Cancer Tip In order to receive the best possible benefit from your cancer therapy, it is important to follow your treatment as your doctor has prescribed. Even if you're not able to visit your regular treatment facility, chances are good that you can still maintain your schedule; many other doctors, nurses, and healthcare providers are able to safely administer your treatment.

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Health Tip The red area in this brain scan shows a pool of blood (a cerebral haemorrhage), which occurs when an artery supplying the brain ruptures and blood seeps out into the surrounding tissue.

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