Cinacalcet - Cinacalcet Drug Information

Indroduction and Uses of Cinacalcet

Cinacalcet is a medicine used to treat hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH). This hormone controls the concentrations of calcium and phosphorus in your blood. Cinacalcet helps lower the amount of PTH which lowers the calcium and phosphorus concentrations.

Cinacalcet is also used to lower calcium in the blood in patients with parathyroid cancer. Cinacalcet hydrochloride belongs to a specific class of agents that lower calcium levels in the blood. It is used to treat hypercalcemia (high calcium level in the blood) caused by cancer of the parathyroid.

Possible Side effects of Cinacalcet

• Diarrhea
• Muscle aches
• Dizziness
• High blood pressure
• Headache
• Nervousness
• Pounding in the ears
• Abdominal cramps 
• Confusion

Dosage and dosing of Cinacalcet

The doses of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

Warning and Precautions of Cinacalcet

• It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
• Cinacalcet hydrochloride lowers the calcium level in your blood. Rarely, the calcium level can get too low (hypocalcemia). Tell your doctor right away if you get numbness and tingling in your hands, feet, or around the mouth; aches in the muscles; cramping; stiffness in your arms or legs; or seizures.
• This medicine may lower the calcium in your blood. The symptoms of low calcium may include abdominal cramps; confusion; convulsions; difficulty in breathing; irregular heartbeats; mood or mental changes; muscle cramps in hands, arms, feet, legs, or face; numbness and tingling around the mouth, fingertips, or feet; shortness of breath; and/or tremor. If you experience any of these symptoms, check with your doctor immediately.

Storage conditions of Cinacalcet

Keep nitulamide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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