Bortezomib

BRAND NAME: Velcade

Indroduction and Uses of Bortezomib

Bortezomib is a cancer chemotherapy drug used to treat certain types of tumors (e.g., multiple myeloma). It blocks certain proteins which helps to slow the growth and spread of the cancer. VELCADE (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Bortezomib is a man-made chemical that is currently used to treat people with multiple myeloma. It is given to people who have already been treated with at least two other types of chemotherapy, and whose myeloma has continued to develop despite other treatments. Bortezomib may also be used to treat other types of cancer as part of a research trial.

Possible Side effects of Bortezomib

• Vomiting
• Anemia
• Headache
• Insomnia
• Edema
• Asthenia
• Nausea
• Diarrhea
• Appetite decreased
• Constipation
• Thrombocytopenia
• Peripheral neuropathy
• Pyrexia

Dosage and dosing of Bortezomib

The doses of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

Warning and Precautions of Bortezomib

• Because bortezomib is known to cause birth defects in an unborn baby, women of childbearing age should not become pregnant during treatment.
• Peripheral neuropathy (nerve problems) is one of the potential side effects of treatment with bortezomib. Contact your healthcare provider immediately if you experience new or worsening symptoms of peripheral neuropathy such as burning sensation, numbness, increased or decreased sensation, pain, or discomfort.
• It is important to drink plenty of fluids while you are being treated with this drug to prevent becoming dehydrated.
• It is not known whether bortezomib passes into breast milk. Do not take bortezomib without first talking to your doctor if you are breast-feeding a baby.

Storage conditions of Bortezomib

Keep nitulamide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Cancer Tip Radiation therapy, or radiotherapy, is a common way to treat cervical cancer. Doctors who specialize in treating cancers with radiation are known as radiation oncologists. During radiation therapy, high-energy x-rays are used to kill cancer cells.

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