Anzemet

Generic Name - Dolasetron

Indroduction and Uses of Anzemet

ANZEMET (dolasetron mesylate) is an antinauseant and antiemetic agent. Dolasetron and its active metabolite, hydrodolasetron (MDL 74156), are selective 5-HT3 receptor antagonists shown not to have activity at other known serotonin receptors and with low affinity for dopamine receptors.

ANZEMET Tablets are indicated for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy, including initial and repeat courses; the prevention of postoperative nausea and vomiting.

Possible Side effects of Anzemet

• Diarrhea
• headache
• Abdominal or stomach pain
• dizziness or lightheadedness
• fever or chills
• unusual tiredness
• Blood in the urine
• chest pain
• decrease in amount of urine
• fast heartbeat
• severe stomach pain with nausea or vomiting
• skin rash
• slow or irregular heartbeat
• troubled breathing

Dosage and dosing of Anzemet

The doses of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

Warning and Precautions of Anzemet

• ANZEMET Tablets are contraindicated in patients known to have hypersensitivity to the drug.
• Dolasetron should be administered with caution in patients who have or may develop prolongation of cardiac conduction intervals, particularly QTc.
• Dolasetron has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies.
• It is not known whether dolasetron passes into the breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.
• Tell your doctor if you have ever had any unusual or allergic reaction to dolasetron. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Storage conditions of Anzemet

Keep nitulamide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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