Anastrozole

Brand Name - Arimidex

Indroduction and Uses of Anastrozole

Anastrozole is a first-line treatment of breast cancer in postmenopausal women. It slows the growth of advanced cancer within the breast and cancer that has spread to other parts of the body. The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex reduces serum concentration of estrogen, an effect that has been shown to be of benefit in postmenopausal women with breast cancer.

Anastrozole is an off-white powder with a molecular weight of 293.4. Anastrozole has moderate aqueous solubility (0.5 mg/mL at 25°C); solubility is independent of pH in the physiological range.

Anastrozole is a man-made drug which is used in the treatment of breast cancer in women who have had their menopause (change of life). It is mainly used to treat women who have advanced breast cancers or breast cancer that has come back after initial treatment (breast cancer that has spread). Sometimes it is used in early breast cancer.

Possible Side effects of Anastrozole

• loss of appetite
• sore throat
• dizziness
• rash
• dry mouth
• swelling of the arms, legs, or ankles (edema)
• depression
• numbness
• vaginal hemorrhage
• weight gain
• sweating
• weakness or tiredness
• upset stomach or vomiting
• headache
• hot flashes
• bone, pelvic, and back pain
• cough
• diarrhea
• constipation
• stomach pain

Dosage and dosing of Anastrozole

The doses of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

Warning and Precautions of Anastrozole

• tell your doctor and pharmacist if you are allergic to anastrozole, povidone, lactose, or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
• tell your doctor if you have or have ever had liver disease, high levels of blood cholesterol, blood clots (thrombophlebitis), or hypertension (high blood pressure).
• if you are premenopausal, tell your doctor if you are pregnant. Anastrozole should not be taken during pregnancy. Therefore, premenopausal women should use a reliable method of birth control. If you become pregnant while taking anatrozole, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking anastrozole.

Storage conditions of Anastrozole

Keep nitulamide in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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